澳门网上十大正规赌场

钱永常

编辑:时间:2018-01-03点击数:

钱永常 博士,男,出生于1962年2月,浙江农林大学特聘教授,浙江农林大学校学术委员会委员,美国Texas A&M大学兼职副教授,浙江省“千人计划”特聘专家,国家林业局铁皮石斛工程技术研发中心副主任,浙江省生物工程学会理事、省毒理学学会理事、省药学会生化药物专业委员会理。

研究方向

中药资源功效成分;神经细胞功能恢复;细胞水平血糖控制;细胞水平免疫调控

工作经历

1991.4-1993.7 美国加州大学戴维斯分校(UC-Davis),植物生理与生化博士后

1993.8-1997.10,美国德州农工大学(Texas A&M),生化与分子生物学博士后

1997.11-1999.10,美国德州农工大学(Texas A&M),生物医学研究员

1999.11-2012.1,美国德州农工大学(Texas A&M),助理教授、副教授

2012.2-至今,美国德州农工大学(Texas A&M),兼职副教授

2012.4-至今,浙江农林大学,特聘教授

学术及科研项目、成果情况

承担教学工作

本科生:Developmental Neurotoxicology;生物制剂与生物检测;化学生物学导论

研究生:Chemical Hazard Assessment;Neuroanatomical Systems: Neurodegenerative Diseases;Neurobiology;化学生物学

科研项目

1.美国德州A&M大学CVM优先计划,  "Lead and Copper Competitively Bind to HMB of ATP7A and GRP78" (项目主任, 25%贡献)

2.美国国立环境与健康研究所项目NIEHS P42 ES04917, “Stress Gene Induction in Mammalian Cells” (项目副主任, 40%贡献)

3.美国国防部项目DOD-CDMRP Concept Award W81XWH-05-1-0163,  "The Function of Neurofibromin in Astrocytes" (项目副主任, 40%贡献)

4.美国德州A&M大学基金, “The Function of Astrocytes in Brain Glucose Utilization” (项目主任, 50% 贡献)

5.美国国立环境与健康研究所项目NIH-NIEHS R21, “Long-Term Monitoring of Dementia-Related Markers in Lead Workers from China” (项目主任, 30% 贡献)

6.浙江农林大学科研发展基金RF2012017,“天然产物功能因子筛选平台的建立”(项目主任,50%贡献)

7.浙江省林业厅省院合作林业科技项目2015SY04,“山核桃神经功能因子挖掘与产品开发的研究”(项目主任,50%贡献)

发表的主要论文

1.Fei Gao, Xiangjun Wang, Aicun Zhou, Evelyn Tiffany-Castiglioni, Lijun Xie, Yongchang Qian(钱永常)* Cellular Evaluation of Anti-tumor Components from Toad Venom. Oncology Letters, in press,2016

2.FeiGao, W.F. Xu, Lingping Tang, Mengmeng Wang, Xiangjun Wang, Yongchang Qian(钱永常)*. Characteristic of cathelicidin-Bg, a novel gene expressed in ear-side gland of Bufo gargarizans. Genetics and Molecular Research, in press, 2016.

3.高  飞,李彤彤,汤玲平,王向军,林莉燕,钱永常*。基于DNA条形码的龙葵系统发育及变异为点分析。中草药,47(1): 114-121, 2016 (abstract in English).

4.李彤彤,高    飞,段承俐,王向军,钱永常*。滇重楼中VEGF结合因子的活性研究。中草药, 46(15): 2251-22562015 (abstract in English).

5.高   飞,周   瑜,王向军,李彤彤,张   宇,黄瑜秋,钱永常*。竹叶提取物抗肿瘤和神经保护作用研究。中草药,46(5): 710-715,2015 (abstract in English).

6.周   瑜,黄坚钦,高   飞,王向军,钱永常*。交联聚乙烯吡咯烷酮(PVPP)对山核桃中多酚去除效果的毒理学评价。食品工业科技, 36(6): 104-108,2015 (abstract in English).

7.Wang Xiang-jun, Wu Huai-xiu, Ye Shan-shan, Pan Lan-ying, Qian Yongchang (钱永常)* Expression of recombinant human acetylcholinesterase and its application in screening inhibitors. Acta Pharmaceutica Sinica, 49 (1): 50-54, 2014

8.Yongchang Qian (钱永常)*, Bingchao Meng, Xuchu Zhang, Ying Zheng, Robert Taylor, Evelyn Tiffany-Castiglioni.HSPA5 Forms Specific Complexes with Copper. Neurochemical Research 38: 321-329, 2013.

9.Tiffany-Castiglioni, E., Qian, Yongchang (钱永常). ER Chaperone-Metal Interactions:  Links to Protein Folding Disorders. Neurotoxicology 33: 545-557, 2012. (7)

10.Qian, Yongchang (钱永常)*, Zheng, Y., Taylor, R., Tiffany-Castiglioni, E. Involvement of the Molecular Chaperone HSPA5 in Copper Homeostasis in Astrocytes. Brain Research 1447: 9-19, 2012. (11)

11.Tiffany-Castiglioni, E., Hong, S., Qian, Yongchang (钱永常). Copper Handling by Astrocytes:  Insights into Neurodegenerative Diseases. International Journal of Developmental Neuroscience 29: 811-818, 2011. (28)

11.Tiffany-Castiglioni, E., Qian, Yongchang (钱永常), Barhoumi, R., Zheng, Y. Determination of Metal Interactions with the Chaperone Hspa5 in Human Astrocytoma Cells and Rat Astrocyte Primary Cultures. Methods in Molecular Biology, 758: 29-48, 2011.

12.Barhoumi, R., Qian, Yongchang (钱永常), Burghardt, R., Tiffany-Castiglioni, E. Image Analysis of Ca2+ Signals as a Basis for Neurotoxicity Assays:  Promises and Challenges. Neurotoxicology and Teratology. 32: 16-24, 2010. (11)

13.Qian, Yongchang (钱永常)*, Zheng, Y, Tiffany-Castiglioni, E. Valproate Reversibly Reduces Neurite Outgrowth by Human SY5Y Neuroblastoma Cells. Brain Research 1302:21-33, 2009. (9)

14.Wang, LJ, Zheng, Y, 钱永常*. 断乳仔鼠器官中铅分布和78000糖调蛋白的变化. 《中华预防医学杂志》第42卷,第10期:731-734页, 2008(abstract in English).

15.White, LD., Cory-Slechta, DA., Gilbert, ME., Tiffany-Castiglioni, E., Zawia, NH., Virgolini, M., Rossi-George, A., Lasley, SM., Qian, Yongchang (钱永常), Basha, MR. New and Evolving Concepts in the Neurotoxicology of Lead. Toxicology and Applied Pharmacology 225: 1-27, 2007.(192)

16.Qian, Yongchang (钱永常)*, Zheng, Y, Weber, D, Tiffany-Castiglioni, E. A 78kD Glucose-Regulated Protein Is Involved In Decrease Of Interleukin-6 Secretion By Lead Treatment From Astrocytes. American Journal of Physiology-Cell Physiology293: C897-C905, 2007. (16)

17.Wang, L. J., Zheng, Y., 钱永常*. 低水平铅暴露对仔鼠白细胞78kd糖调蛋白表达的影响. 《国际医药卫生导报》第13卷,第12期:8-12页,2007(abstract in English).

18.Falahatpisheh, H., Nanez, A., Montoya-Durago, D., Qian, Yongchang (钱永常), Tiffany-Castiglioni, E., Ramos, KS. Activation Profiles of HSPA5 During the Glomerular Mesangial Cell Stress Response to Chemical Injury. Cell Stress & Chaperones 12: 209-218, 2007. (13)

19.Barhoumi, R., Burghardt, R., Qian, Yongchang (钱永常), Tiffany-Castiglioni, E. Effects of propofol on intracellular Ca2+ homeostasis in human astrocytoma cells. Brain Research 1145: 11-18, 2007. (19)

20.Qian, Yongchang (钱永常), Venkatraj, J., Barhoumi, R., Pal, R., Datta, A., Wild, J. R., Tiffany-Castiglioni, E. Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) human neuroblastoma and astrocytoma cell lines. Toxicology and Applied Pharmacology219: 162-171, 2007. (16)

21.Tiffany-Castiglioni, E., Hong, S., Qian, Yongchang (钱永常), Tang, Y., Donnelly, K.C.  COMMENTARY:  In Vitro Models for Assessing Neurotoxicity of Mixtures. Neurotoxicology 27: 835-839, 2006. (20)

22.Tiffany-Castiglioni, E., Venkatraj, J.S., Qian, Yongchang (钱永常).  Genetic polymorphisms and mechanisms of neurotoxicity:  overview.  Neurotoxicology 26: 641-649, 2005.

23.Qian, Yongchang (钱永常)*, Zheng, Y., Ramos, K.S., Tiffany-Castiglioni, E. The Involvement of Copper Transporter in Lead-induced Oxidative Stress in Astroglia. Neurochemical Research 30: 429-438, 2005. (27)

24.Qian, Yongchang (钱永常)*, Zheng, Y., Abraham, L., Ramos, K.S., Tiffany-Castiglioni, E. Differential Profiles of Copper-induced ROS Generation in Human Neuroblastoma and Astrocytoma Cells. Molecular Brain Research 134: 323-332, 2005. (30)

25.Qian, Yongchang (钱永常)*, Zheng, Y., Ramos, K.S., Tiffany-Castiglioni, E. GRP78 compartmentalized redistribution in pb-treated glia: role of grp78 in lead-induced oxidative stress. Neurotoxicology26: 267-275, 2005. (45)

出版专著

1.Yongchang Qian(钱永常)*,Evelyn Tiffany-Castiglioni. Lead-Induced Developmental Neurotoxicity and Modulated Gene Expression. In: Comprehensive Toxicology, Third Edition. Charlene A. McQueen (ed.). Elsevier, 2016, pp. xxx.

2.Yongchang Qian(钱永常)*, Linjing Wang, Evelyn Tiffany-Castiglioni. Lead-Modulated Gene Expression in the Central Nervous System. In: Reference Module in Biomedical Sciences Reviews. Michael Caplan (ed). Elsevier, 2014, pp. 29

3.Qian, Yongchang (钱永常). Heavy Metal-Regulated Gene Expression in the Nervous System. In: Comprehensive Toxicology, Second Edition. Kenneth S. Ramos (ed.). Elsevier, Oxford, 2010, pp. 495-521.

4.Tiffany-Castiglioni, E., Venkatraj, J.S., Qian, Yongchang (钱永常), Wild, J.R.   Chapter 22 In vitro models for testing organophosphate-induced neurotoxicity and remediation.  In:  Toxicology of Organophosphate & Carbamate Pesticides, Ramesh C. Gupta (ed).  Elsevier, Amsterdam, 2006, pp. 315-337.

5.Tiffany-Castiglioni, E., Qian, Yongchang (钱永常). Chapter 26 Astroglia and Lead Neurotoxicity. In: The Role of Glia in Neurotoxicity, Second Edition. M. Aschner, L. G. Costa (eds), CRC Press, Boca Raton, FL, 2005, pp. 417-437.

6.Tiffany-Castiglioni, E., Qian, Yongchang (钱永常). Cell-Type Specific Responses of the Nervous System to Lead. In: Methods in Pharmacology and Toxicology: In Vitro Neurotoxicology: Principles and Challenges. E. Tiffany-Castiglioni (ed), Humana Press Inc., Totowa, NJ, 2004, pp.151-186

7.Harris, E. D., Reddy, M. C. M., Qian, Yongchang (钱永常), Tiffany-Castiglioni, E., Majumdar, S., Nelson, J. Multiple forms of the Menkes Cu-ATPase. In: Leone, A., Mercer, J. F. B. (Ed.), Copper Transport and Its Disorders. Kluwer Academic/ Plenum Publishers, New York, 1999, pp. 39-51.

8.Harris, E.D., Tiffany-Castiglioni, E., Qian, Yongchang (钱永常).  Copper in cell culture.  In: Trace Element in Laboratory Rodents: Nutritional Research Methods, R.R. Watson (ed), CRC Publishers, Boca Raton, FL, 1996, pp.163-187

获奖情况

1.美国毒理学会Gulf Coast分会优秀博士后奖

2.浙江省“千人计划”创业人才

3.浙江省杭州市萧山区“优秀留学人员创业人才”

4.浙江省杭州市萧山区“十佳优秀科技人才”

5.浙江省杭州市萧山区首届“爱乡名士”

联系方式

联系地址:澳门网上十大正规赌场,浙江杭州临安,311300

电  话:15988453541

电子邮件:qian3906@zafu.edu.cn

   地址:浙江省杭州市临安区武肃街666号学6       邮编:311300         Copyright 2019 澳门网上十大正规赌场      技术支撑:西安博达App股份有限企业

 

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